This design comes from season 10 episode 2 called “The Wizard of Evergreen Terrace”. Despite accomplishing much more than most people will in their lifetime, Homer has a crisis that he’s wasted his life. He becomes a bit depressed, then learns of Thomas Edison the inventor. In an attempt to living a fulfilled and meaningful life (again, despite a massive amount of achievements by this point) he follows Edison’s footsteps and tries his hand at being an inventor. When walking through the souvenir shop at the Edison Museum a shirt in the background is shown saying “Screw this” which I thought would make a perfect addition to my shop given my attitude towards most things in life.

Here’s the link to the product as a sticker, but you can view the design on multiple items if you’re interested.